Overview

Scholarly Activities

(Representative from the last two years)

 

GRANTS

Puglisi, J. COM Mini-Grant Program. Project: LabHEART Quattro: A Computer Model to Study Cardiac Electrophysiology. January 2nd-December 31st, 2017. Total: $5,000.

 

Bradbury, M. COM Mini-Grant Program. Project: Modulation of Hepatoma Gene Expression Patterns by Substrate and Culture Conditions: A Model for Hepatocyte Response to Environmental Conditions. January 2nd-December 31st, 2017. Total: $10,000.

 

Feng, X. COM Mini-Grant Program. Project: Assessing Risks of Impaired Healing and Osteomyelitis Associated with Bisphosphonates. January 2nd-December 31st, 2017. Total: $4,500.

 

Gerriets, V. COM Mini-Grant Program. Project: The role of serotonin in T cell differentiation and function. January 2nd-December 31st, 2017. Total: $10,000.

 

Khaira, K. COM Mini-Grant Program. Project: Concussion Awareness, Prevention and Treatment January 2nd-December 31st, 2017. Total: $4,000.

 

Arias, H.R. COM Mini-Grant Program. Project: Positive allosteric modulators of α7 nicotinic receptors for cognitive impairments. January 2nd-December 31st, 2017. Total: $6,500.

 

Arias, H.R. (Co-PI). The Åhlen Foundation, Sweden. Project: Experimental strategies for improvement of pharmacological treatment in schizophrenia by selective α7 nicotinic receptor ligands: focus on cognition. International Scientific collaboration with Dr. Marie-Louis Wadenberg, Faculty of Health & Life Sciences, Linnaeus University, Kalmar, Sweden. February, 2015-December 31st, 2016. Total: 100,000 SEK.

 

Arias, H.R. (Co-PI). SONATA funding, National Science Centre, Poland. Project: Analysis of the structural and functional mechanisms of action of nicotinic receptor modulators. International Scientific collaboration with Dr. K. Targowska-Duda, Laboratory of Medicinal Chemistry and Neuroengineering, Department of Chemistry, Medical University of Lublin, Lublin, Poland. March, 2014-February, 2017. Total: 461.950 PLN.

 

 

PUBLICATIONS

Jialal, I., Adams-Huet, B., Major, A., and Devaraj, S. (2017) Increased fibrosis and angiogenesis in subcutaneous gluteal adipose tissue in nascent metabolic syndrome. Diabetes Metab., in press.

Pahwa, R., Adams-Huet, B., and Jialal, I. (2017) The effect of increasing body mass index on cardio-metabolic risk and biomarkers of oxidative stress and inflammation in nascent metabolic syndrome. J. Diabetes and Complications, in press.

Jialal, I., Inn, M., Siegel, D., Devaraj, S. (2017) Underestimation of low density lipoprotein-cholesterol with the Friedewald equation versus a direct homogenous low density lipoprotein-cholesterol assay. In press.

Lizza, J.R., Patel, S.V., Yang, C.F., and Moura-Letts, G. (2016) DPP4 Inhibitors: Direct Synthesis of Cyanopyrrolidinyl _-Amino Alcohols for the Development of Diabetes Therapeutics. Eur. J. Org. Chem. 2016, 5160-5168.

Yin, A.C., Goldberg, K.H., Mupparapu, A., Retzbach, E.P., Yin, K., Yang, C.F., and Goldberg, G.S. (2016) Low Molecular Weight Components in Aqueous Echinacea Purpurea Leaf Extract Inhibit Melanoma Cell Growth. J. Cancer Biol. Ther. 1, 109-117.

Duell, P.B. and Jialal, I. (2016) Modern management of familial hypercholesterolemia. Metab. Syndr. Relat. Disord. 14, 463-467.

Chinn, M., Cohen, H., Averick, A., Ismail, Z., and Feng, X. (2016) Cancer Biosimilars: Regulation Challenges and Clinical Impact. US Pharm. 41 (Specialty & Oncology suppl.), 7-12.

Anders, U.M., Cho, M.J., Martel, J.R., and Martel, J.B. (2016) Invasive Orbital Xanthogranuloma. EC Ophthalmology 4.2, 495-497.

Goldstein, M.H., Martel, J.R., Sall, K., Goldberg, D.F., Abrams, M., Rubin, J., Sheppard, J., Tauber, J., Korenfeld, M., Agahigian, J., Durham, T.A., Furfine. E. (2016) Multicenter Study of a Novel Topical Interleukin-1 Receptor Inhibitor, Isunakinra, in Subjects With Moderate to Severe Dry Eye Disease. Eye & Contact Lens. 0, 1-10.

Potasiewicz, A., Hołuj, M., Kos, T.,  Popik, P., Arias, H.R., and Nikiforuk, A. (2016) 3-Furan-2-yl-N-p-tolyl-acrylamide, a positive allosteric modulator of the α7 nicotinic receptor, reverses schizophrenia-like cognitive deficits in rats. Neuropharmacology 113 (Part A), 188-197.

Arias, H.R., Feuerbach, D., and Ortells, M. (2016) Bupropion and its photoreactive analog (±)-SADU-3-72 interact with luminal and non-luminal sites at human α4β2 nicotinic acetylcholine receptors. Neurochem. Int. 100, 67-77.

Anders, U.M., Taylor, E.J., Martel, J.R., and Martel, J.B. (2016) Pseudo-Orbital Apex Syndrome in the Acute Trauma Setting Due to Ipsilateral Dissection of Internal Carotid Artery. Ophthal. Plast. Reconstr. Surg. 32, e96-7.

Zhang, Y., Dennis Somtakoune, S., Cheung, C., Listiawan, M., and Feng, X. (2016) Therapeutic Application of Pharmacogenomics in Oncology. AAPS J. 18, 819-829.

Fuenzalida, M., Pérez, M.A., and Arias, H.R. (2016) Role of nicotinic and muscarinic receptors on synaptic plasticity and neurological diseases. Curr. Pharm. Des. 22, 2004-2014 (Thematic issue: Effective and promising treatments for neurological disorders and cancer; Uteshev, V., Ed.).

Arias, H.R., Ravazzini, F., Targowska-Duda, K.M., Kaczor, A.A., Feuerbach, D., Boffi, J.C., Draczkowski, P., Montag, D., Brandon, M.B., Elghoyen, A.B., Jozwiak, K., and Puja, G. (2016). Positive allosteric modulators of α7 nicotinic acetylcholine receptors affect neither the function of ligand- and voltage-gated ion channels and acetylcholinesterase, nor β-amyloid content.  Int. J. Biochem. Cell Biol. 76, 19-30.

Arias, H.R. (2016) Introduction to the special issue “functional and therapeutic aspects of the nicotinic acetylcholine receptor family”. Neurotransmitter 3, e1306 (2 pages) (Arias, H.R., Ed.).

Atzori, M., García-Oscos, F., and Arias, H.R. (2016) α7 nicotinic acetylcholine receptor-mediated anti-inflammatory actions modulate brain functions. Neurotransmitter 3, e1303 (15 pages) (Special Issue: Functional and therapeutic aspects of the nicotinic acetylcholine receptor family; Arias, H.R., Ed.).

García-Colunga, J., Targowska-Duda, K.M., and Arias, H.R. (2016) Functional and structural interactions between selective serotonin reuptake inhibitors and nicotinic acetylcholine receptors. Neurotransmitter 3, e1293 (11 pages) (Special Issue: Functional and therapeutic aspects of the nicotinic acetylcholine receptor family; Arias, H.R., Ed.).

Andersen, N.D., Nielsen, B.E., Corradi, J., Tolosa, M.F., Feuerbach, D., Arias, H.R., and Bouzat, C. (2016) Exploring the positive allosteric modulation of human α7 nicotinic receptors from a single-channel perspective. Neuropharmacology 107, 189-200.

Dennis Somtakoune, S., Zhang, Y., Todd, M.P., Cohen, H., and Feng, X. (2016) Cancer Vaccines and Immunotherapy for Tumor Prevention and Treatment. US Pharm. 40, 13-18 (Specialty Pharmacy and Oncology Supplement).

Targowska-Duda, K.M., Wnorowski , A., Budzynska, B., Jozwiak, K., Biała, G., and Arias, H.R. (2016) The positive allosteric modulator of α7 nicotinic acetylcholine receptors, 3-furan-2-yl-N-p-tolyl-acrylamide, enhances memory processes and stimulates ERK1/2 phosphorylation in mice. Behav. Brain Res. 302, 142-151.

Jey, A., Hull, P., Kravchuk, V., Carrillo, B., and Martel, J.B. (2016) Emergent diagnosis and management of TASER penetrating ocular injury. Am. J. Emerg. Med. 34, 1740.e3-5.

 

 

BOOKS and BOOK  CHAPTERS

 

Castellon, M.G., Lui, F.S., and Levy, M. (2017) Vascular Neurology. Statpearls Publishing.

Listiawan, M., Feng, M., and Feng, X. (2016) Clinical Applications of Pharmacogenomics in Cancer Therapy. In Applying Pharmacogenomics in Therapeutics (Feng, X. and Xie, H-G., Eds.), pp.143-180.

Listiawan, M., and Feng, X. (2016) Therapeutic Application of Pharmacogenomics in Cancer Treatment: Toxicity Prediction and Minimization. (Feng, X. and Xie, H-G, Eds.). Therapeutic Application of Pharmacogenomics in Patient Care. Taylor & Francis, ISBN: 978-1-4665-8267-5. In press.

 

AWARDS 

 

Hall, M., Kolb, J., Todd Jr., B., Pugh, D., Vance, B., Klienstuber, B., Drecketts, R., Jackson, D., Arias, H.R., and Sudweeks, S.N., 12th Annual Mary Lou Fulton Mentored Student Research Conference, Brigham Young University, Provost, UT, April 7th, 2016. 1st prize for the Neuroscience poster entitled “PAMs: A growing field in pharmacological drug development”.

Craddock, M., Targowska-Duda, K.M., Budzynska, B., Michalak, A., Loland, C.J., Jozwiak, K., Biała, G., and Arias, H.R., CNU Research Day, Elk Grove, CA, January 20th, 2017. Best poster, entitled “Selective positive allosteric modulators of a7 nicotinic receptors have antidepressant-like activity”.

Sheehan, K., and DiSibio, G., CNU Research Day, Elk Grove, CA, January 20th, 2017. Best oral presentation, entitled “Novel Methods of Medical Education - Clinical Cases as Preparation for the Wards and Beyond”.

California Northstate University College of Medicine ♦ 9700 West Taron Drive ♦ Elk Grove, CA 95757 ♦ Phone: (916) 686-7400