Research Centers

Alexies Dagnino, PhD

Academic Title
Professor of Neuroscience
Laboratory of Behavioral Neurobiology, Faculty of Sciences
Universidad de Valparaíso, Chile

Contact Information
Office Phone: +56 32 250 8059

Research Projects:
Neurobiology of stress and major depression. Anti-stress and antidepressant effects of polyunsaturated fatty acid and endocannabinoids.

Current Grants:
2014-2018 “Effects of ω-3 fatty acids and endocannabinoids on learning and auditory attention of chronically stressed rats”. Principal Investigator. Supported by: FONDECYT Regular Nº 1141276.

2013-2016 “Regulation of long-term plasticity at inhibitory circuits by acetylcholine: new role of parvalbumin-positive interneurons in the hippocampal function and memory”. Co-Investigator. Supported by: FONDECYT Regular Nº 1130614.

Publications (most representatives from the last 3 years):
Pérez MÁ, Ahumada J, Fuenzalida M, Dagnino-Subiabre A. 2015. Omega-3 fatty acid supplementation improves stress-induced impairments to memory and GABAergic synaptic efficacy in the rat hippocampus. Neural Plasticity, ID: 562597. Under Review.

Negrón-Oyarzo I, A, Dagnino-Subiabre A, Muñoz P. 2015. Stress-induced synaptic impairments during adolescence are reversed at adulthood. Frontiers in Cellular Neuroscience. Under Review.

Cruz G, Riquelme R, Espinosa P, Jara P, Dagnino-Subiabre A, Renard GM, Sotomayor-Zárate R. 2014. Neonatal exposure to estradiol valerate increases dopamine content in nigrostriatal pathway during adulthood in the rat. Horm Metab Res. 46(5):322-7.

Negrón-Oyarzo I, Pérez MA, Terreros G, Muñoz P, Dagnino-Subiabre A. 2014. Effects of chronic stress in adolescence on learned fear, anxiety, and synaptic transmission in the rat prelimbic cortex. Behav Brain Res. 259:342-53.

Pérez MA, Terreros G, Dagnino-Subiabre A. 2013. Long-term omega-3 fatty acid supplementation induces anti-stress effects and improves learning in rats. Behav Brain Funct. 9(1):25.

Pérez MÁ, Pérez-Valenzuela C, Rojas-Thomas F, Ahumada J, Fuenzalida M, Dagnino-Subiabre A(*). 2013. Repeated restraint stress impairs auditory attention and GABAergic synaptic efficacy in the rat auditory cortex. Neuroscience. 246C:94-107.

Dagnino-Subiabre A(*). 2013. Effects of chronic stress on the auditory system and fear learning: an evolutionary approach. Reviews in the Neurosciences. 24(2):227-237.

Dagnino-Subiabre A(*), Pérez MA, Terreros G, Cheng MY, House P, Sapolsky MR. 2012. Corticosterone Treatment Impairs Auditory Fear Learning and the Dendritic Morphology of the Rat Inferior Colliculus. Hearing Research. 294(1-2):104-113.

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